ADB is down in Android

ADB is down in Android

I am getting this exception when i trying to run my application
[2013-09-10 12:09:21 - EffectiveNavigation] The connection to adb is down,
and a severe error has occured.
[2013-09-10 12:09:21 - EffectiveNavigation] You must restart adb and Eclipse.
[2013-09-10 12:09:21 - EffectiveNavigation] Please ensure that adb is
correctly located at
'E:\Configured-Eclipse\adt-bundle-windows-x86-20130522\sdk\platform-tools\adb.exe'
and can be executed.
When i tried to reset adb from eclipse it is showing this error
[2013-09-10 12:18:20 - adb] Attempting to restart adb, but version check
failed!
I have tried this also from the command prompt.
1.adb kill-server //kill all active server
2.adb start-server //start adb server
Restarted the eclipse also but still the same error .Help me to resolve
the issue.